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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3B1
All Species:
13.64
Human Site:
S190
Identified Species:
25
UniProt:
O75533
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75533
NP_036565.2
1304
145830
S190
V
V
N
G
A
A
A
S
Q
P
P
S
K
R
K
Chimpanzee
Pan troglodytes
XP_516006
1379
153963
S265
V
V
N
G
A
A
A
S
Q
P
P
S
K
R
K
Rhesus Macaque
Macaca mulatta
XP_001086317
1397
156322
S283
V
V
N
G
A
A
A
S
Q
P
P
S
K
R
K
Dog
Lupus familis
XP_857149
1312
146628
R198
Q
P
P
S
K
R
K
R
R
W
D
Q
T
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99NB9
1304
145798
S190
V
V
N
G
A
A
A
S
Q
P
P
S
K
R
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421912
1383
154834
A269
L
K
V
V
N
G
A
A
S
Q
P
P
S
K
R
Frog
Xenopus laevis
O57683
1307
146196
P193
S
A
S
S
A
A
Q
P
P
S
K
R
K
R
R
Zebra Danio
Brachydanio rerio
XP_684311
1315
147162
R201
A
A
A
K
R
K
R
R
W
D
Q
T
A
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623732
1315
147662
N184
K
E
G
T
L
K
A
N
G
E
P
K
P
A
P
Nematode Worm
Caenorhab. elegans
NP_497853
1322
147305
H183
R
A
K
A
G
E
L
H
V
T
G
Q
P
E
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002323970
1267
141858
A163
K
K
K
E
E
E
E
A
R
A
E
K
G
D
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_201232
1269
141432
K162
R
L
I
A
K
K
K
K
E
E
E
E
A
A
A
Baker's Yeast
Sacchar. cerevisiae
P49955
971
110009
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
93.3
99.3
N.A.
99.9
N.A.
N.A.
N.A.
93.7
96.6
93.7
N.A.
N.A.
82.4
65.1
N.A.
Protein Similarity:
100
94.5
93.3
99.3
N.A.
100
N.A.
N.A.
N.A.
93.7
98.3
96.4
N.A.
N.A.
88.9
76.6
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
N.A.
N.A.
N.A.
13.3
26.6
0
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
100
N.A.
N.A.
N.A.
40
40
13.3
N.A.
N.A.
20
6.6
N.A.
Percent
Protein Identity:
68.4
N.A.
N.A.
68.3
40.4
N.A.
Protein Similarity:
79.3
N.A.
N.A.
79.1
53.1
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
8
16
39
39
47
16
0
8
0
0
16
24
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
8
0
0
16
8
% D
% Glu:
0
8
0
8
8
16
8
0
8
16
16
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
31
8
8
0
0
8
0
8
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
16
16
16
8
16
24
16
8
0
0
8
16
39
8
47
% K
% Leu:
8
8
0
0
8
0
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
31
0
8
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
8
0
0
0
0
8
8
31
47
8
16
0
8
% P
% Gln:
8
0
0
0
0
0
8
0
31
8
8
16
0
0
8
% Q
% Arg:
16
0
0
0
8
8
8
16
16
0
0
8
0
39
16
% R
% Ser:
8
0
8
16
0
0
0
31
8
8
0
31
8
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
8
0
8
8
0
0
% T
% Val:
31
31
8
8
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _